New discovery: combination of antimalarial drugs and antibiotics can shorten treatment cycle for COVID-19

A recent French study suggests that treating patients with COVID-19 with a combination of antimalarials and antibiotics may be an effective weapon against the new coronavirus.
New discovery: combination of antimalarial drugs and antibiotics can shorten treatment cycle for COVID-19

The study, published in the International Journal of Antimicrobial Drugs, researchers earlier this month prescribed antimalarial drugs hydroxychloroquine and the antibiotic azithromycin.


The researchers said in the report: "Patients with confirmed COVID-19 in France were enrolled in the one-arm regimen from early March to March 16, receiving 600 mg of chlor chloroquine daily and testing the viral load in their nasopharyngeal swabs daily in a hospital setting. Add azithromycin to the treatment based on their clinical manifestations. "

Untreated patients and refusal COVID-19 cases from another center served as negative controls. The researchers explained: "On day 6 after joining, the presence or absence of the virus will be considered the final diagnosis."

Six patients in the study were asymptomatic, 22 had symptoms of upper respiratory tract infection, and 8 had symptoms of lower respiratory tract infection. Researchers treated 20 cases in the study. These cases show that compared to the control group, viral carrying was significantly reduced after D6-post was included, and the average carrying time was much lower than untreated patients in the literature.

The researchers added: " Adding azithromycin to hydroxychloroquine can significantly improve virus clearance. Although the sample size is small, our investigation showed that chlor chloroquine treatment was significantly associated with a reduction or disappearance of viral load in patients with COVID-19, Azithromycin enhances its effect. "

The study was led by Philippe Gautret and Jean-Christophe Lagier of the Institute of Infectious Diseases of the University of Marseille and Aix-Marseille.

Dr Mehmet Oz also recently stated that he is optimistic about the French study data and explained: "These drugs are very effective in reducing the viral load of COVID-19 in patients with coronavirus. If this is true, We can actually make this virus behave more like the flu virus. "

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